Age-related macular degeneration is a condition in which the macula – the central part of the retina at the back of your eye – gradually deteriorates. The macula is responsible for your sharp, central vision and for perceiving colours and fine details. In macular degeneration, the light-sensitive cells in this area become damaged, causing your central vision to become blurred or distorted.
The condition mainly affects people over the age of fifty and is therefore also known as age-related macular degeneration, abbreviated to AMD. It is one of the most common causes of severe vision loss among older people in Western countries.
Dry and wet AMD
There are two main forms of age-related macular degeneration: dry AMD and wet AMD. Dry AMD is the most common form and develops slowly. In this condition, waste products build up beneath the retina, leading to a thinning of the macula. Wet AMD is less common but develops more rapidly. In this form, abnormal blood vessels grow beneath the retina and start to leak or bleed, which can lead to more rapid damage to the macula.
Symptoms
Early symptoms of age-related macular degeneration include blurred central vision, distorted lines (straight lines appear bent or wavy), difficulty reading or recognising faces, and reduced colour perception. Peripheral vision is usually preserved, which means that AMD rarely leads to complete blindness. The symptoms may start in one eye and later develop in the other eye as well.
Causes and risk factors
The exact cause of age-related macular degeneration is not fully understood, but a combination of factors plays a role. Age is the main risk factor: the older you get, the greater the risk. Heredity also plays a part; if AMD runs in your family, your risk is increased. Other factors associated with a higher risk include smoking, high blood pressure, being overweight, prolonged exposure to sunlight, and a diet low in certain nutrients such as omega-3 fatty acids and antioxidants.